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1.
Plast Reconstr Surg Glob Open ; 9(7): e3711, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34422526

RESUMO

Eyelid dermatochalasis is an abnormal distention of the upper eyelid. This article presents a new classification of the lateral dermatochalasis (LDC) of the upper eyelids, which compares the pre- and post-blepharoplasty results and matches its results with those of the well-established Jacobs classification (JEC). METHODS: LDC classification includes four degrees: grade zero-absence of dermatochalasis; grade 1-lower edge of dermatochalasis above the intersection of the lacrimal caruncle with the edge of the upper eyelid; grade 2-between the intersection of the lacrimal caruncle with the edge of the upper eyelid and the lower edge of the iris at the pupillary midpoint; and grade 3-lower edge of dermatochalasis below the lower edge of the iris. This study was conducted in 100 dermatochalasis cases in patients between 38 and 79 years of age (mean = 59.3) and submitted to upper blepharoplasty. RESULTS: No statistically significant association was found between the LDC and JEC methods (P = 0.583). In both classifications, the eyelid dermatochalasis was reduced after blepharoplasty (P < 0.001). However, changes in the degrees of dermatochalasis before blepharoplasty were detected in 100% by LDC, and 41% by JEC. The degree of improvement of dermatochalasis observed by LDC after blepharoplasty showed greater specificity. CONCLUSIONS: This new classification, LDC, is specific for the lateral eyelid dermatochalasis, which is based on exact anatomical points, and is easy to perform. LDC is superior to JEC, easy to be applied, and effective and specific in detecting variations in dermatochalasis after blepharoplasty.

2.
J. Bras. Patol. Med. Lab. (Online) ; 57: e2682021, 2021. tab
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1350874

RESUMO

ABSTRACT Introduction: Squamous cell carcinoma (SCC) is the most common tumor among all cancers in the oral cavity. Despite advances, the prognosis of this neoplasm remains a challenge for professionals. Faced with this situation, several studies try to associate the histopathological analysis with prognosis, so that therapeutic planning becomes more accurate. Objectives: This research aimed to conduct an epidemiological study of oral SCC and classify them histopathological assessment according to the World Health Organization (WHO) and the Budding and Depth of Invasion (BD) model. A retrospective research was conducted. Methodology: Data from medical records filed at UOPECCAN Hospital between 2009 and 2015 were analyzed. The sample consisted of 57 patients. Epidemiological data were collected and the blocks were rescued and cut for histopathological analysis. Associations were performed using the chi-square test with a significance level of 5% (p = 0.05) by the GraphPad Prism program. The two histopathological analyzes were correlated using Spearman's statistical test. Results: After analyzing the samples, we found a higher prevalence of oral SCC in male smokers aged above 40 years. There was no correlation between the BD and WHO methods. The WHO classification was significantly associated with age (p = 0.03), and follow-up care (p = 0.05). However, the BD model associated lymph node involvement (p = 0.005) and clinical staging (p = 0.005). Conclusion: The BD classification was more objective for histopathological analysis and may be an important tool for analyzing patient prognosis, assisting in the treatment decision.


RESUMEN Introducción: El carcinoma de células escamosas (CCE), denominado además carcinoma epidermoide, es el tumor más común entre todos los cánceres de la cavidad oral. A pesar de los avances, el pronóstico de esta neoplasia sigue siendo un desafío para los cirujanos/profesionales/clínicos. Ante esta situación, varios estudios intentan asociar el análisis histopatológico con el pronóstico, para que la planificación terapéutica sea más precisa. Objectivos: Esta investigación tuvo como objetivo realizar un estudio epidemiológico del CCE oral y clasificarlo histopatológicamente de acuerdo con la Organización Mundial de la Salud (OMS) y el modelo Budding and Depth of Invasion (BD). Se realizó una investigación retrospectiva. Metodología: Se analizaron los datos de las historias clínicas archivadas en el Hospital UOPECCAN entre 2009 y 2015. La muestra estuvo formada por 57 pacientes. Se recolectaron datos epidemiológicos y los bloques fueron rescatados y cortados para análisis histopatológico. Las asociaciones se realizaron mediante la prueba de chi-cuadrado con un nivel de significancia del 5% (p = 0.05) por el programa GraphPad Prism. Los dos análisis histopatológicos se correlacionaron mediante la prueba estadística de Spearman. Resultados: Tras analizar las muestras, encontramos una mayor prevalencia de CCE oral en varones fumadores mayores de 40 años. No hubo correlación entre los métodos BD y OMS. La clasificación de la OMS se asoció significativamente con la edad (p = 0,03) y seguimiento del del tratamiento (p = 0,05). Sin embargo, el modelo de BD asoció la afectación de los ganglios linfáticos (p = 0,005) y la estadificación clínica (p = 0,005). Conclusión: La clasificación BD fue más objetiva para el análisis histopatológico y puede ser una herramienta importante para analizar el pronóstico del paciente, asistiendo en la decisión del tratamiento.


RESUMO Introdução: O carcinoma de células escamosas (CCE) é o tumor mais frequente entre todos os cânceres localizados na cavidade bucal. Apesar dos avanços, o prognóstico dessa neoplasia ainda é um desafio para os cirurgiões. Diante dessa situação, vários estudos tentam associar a análise histopatológica ao prognóstico, a fim de que os planejamentos terapêuticos se tornem mais precisos. Objetivos: Esta pesquisa teve como objetivo realizar o estudo epidemiológico dos CCEs e classificá-los histopatologicamente conforme a Organização Mundial da Saúde (OMS) e o modelo "Budding and Depth of Invasion" (BD). Um estudo retrospectivo foi realizado. Metodologia: Foram analisados dados dos prontuários arquivados no Hospital UOPECCAN entre 2009 e 2015. A amostra foi composta por 57 pacientes. Os dados epidemiológicos foram coletados e os blocos resgatados e cortados para análise histopatológica. As associações foram realizadas por meio do teste qui-quadrado, com nível de significância de 5% (p = 0,05) pelo programa GraphPad Prism. As duas análises histopatológicas foram correlacionadas por meio do teste estatístico de Spearman. Resultados: Após análise das amostras, verificamos mais prevalência de CCE nos pacientes fumantes do sexo masculino com idade superior a 40 anos. Não houve correlação entre os métodos BD e OMS. A classificação da OMS apresentou associação significante com a idade (p = 0,03) e a sequência de tratamento (p = 0,05). Já o modelo BD associou comprometimento linfonodal (p = 0,005) e estadiamento clínico (p = 0,005). Conclusão: A classificação BD foi mais objetiva para a análise histopatológica e pode ser uma importante ferramenta para análise do prognóstico do paciente, auxiliando na decisão do tratamento.

3.
Obes Surg ; 29(10): 3195-3201, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31077026

RESUMO

INTRODUCTION: Food intolerance is expected during the postoperative period following gastric bypass and may be associated with inadequate chewing. OBJECTIVE: To evaluate chewing before and after speech therapy intervention in subjects undergoing Roux-en-Y gastric bypass who present with food intolerance. MATERIALS AND METHODS: This was a randomized controlled trial, approved by the Brazilian Ethics and Research Committee under n. 438,600. The study population was allocated into two groups: the study group (SG), who received speech therapy intervention, and the control group (CG), who did not receive any intervention, in six visits at 7, 15, 30, 60, and 90 days (v7, v15, v30, v60, and v90) after the initial visit (v0). During v0 and v90, a chewing evaluation was performed according to the MBGR protocol adapted. The significance level adopted was 5%. RESULTS: A total of 30 females (88%) and 4 males (12%) were analyzed. The SG had 18 subjects, and the CG had 16, with mean ages of 50.17 ± 12.28 years and 45.69 ± 9.78 years, respectively. The postoperative time ranged from 4 to19 months. In the SG, a marked improvement in the number of episodes of food intolerance was observed (p < 0.001), an improvement in the intake of cereals and meats (p = 0.004 and p < 0.001, respectively), and an improvement in chewing capacity and swallowing (p = 0.002 and p = 0.011, respectively). CONCLUSION: Speech therapy intervention in chewing led to a marked improvement of food acceptance and food intolerance resulting from Roux-en-Y gastric bypass.


Assuntos
Intolerância Alimentar/etiologia , Derivação Gástrica/efeitos adversos , Mastigação/fisiologia , Obesidade Mórbida/cirurgia , Fonoterapia/métodos , Adulto , Idoso , Deglutição/fisiologia , Dieta , Feminino , Intolerância Alimentar/diagnóstico , Intolerância Alimentar/fisiopatologia , Intolerância Alimentar/terapia , Derivação Gástrica/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Período Pós-Operatório
4.
Parasitol Res ; 116(7): 2047-2051, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28508164

RESUMO

Strongyloidiasis is the most clinically important disease among the infections caused by geohelminths, seeing that this parasite can cause autoinfection. The use of nematophagous fungi like Duddingtonia flagrans, that have predation action on eggs and infecciososas forms of helminths, emerges as an alternative method for environmental control. For this reason, analyzing the viability of larvae and eggs of Strongyloides venezuelensis and the action of Duddingtonia flagrans AC001 in vermiculite, as well as the action of the nematophagous fungi in different growth stages, is important to elaborate and define the best culture conditions that favor the activity of the fungus. Two different growth conditions were applied: both eggs and AC001 fungi were added at the same time to the vermiculite (assay A) and the addition of eggs after the growth of the AC001 fungi in the vermiculite (assay B). To recover the L3 larvae, the Baermann-Moraes method was applied, followed by the counting of L3 dead and alive. At last, it was observed that the vermiculite enriched with organic material is an adequate culture medium not only for the growth of the S. venezuelensis but also for the growth of the D. flagrans fungus, being therefore, a satisfactory culture medium for tests of viability and predatory action of this fungus. It was also observed that the activity of the AC001 fungus is greater when it is growing concomitantly with the eggs, in other words, when it is in the adaptation phase.


Assuntos
Silicatos de Alumínio , Duddingtonia/fisiologia , Óvulo/fisiologia , Strongyloides/fisiologia , Animais , Fezes , Larva/microbiologia , Larva/fisiologia , Controle Biológico de Vetores/métodos
5.
Case Rep Surg ; 2016: 3176842, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27597923

RESUMO

Introduction. Bloom syndrome (BS) is an inherited disorder due to mutation in BLM gene. The diagnosis of BS should be considered in patients with growth retardation of prenatal onset, a photosensitive rash in a butterfly distribution over the cheeks, and an increased risk of cancer at an early age. Clinical manifestations also include short stature, dolichocephaly, prominent ears, micrognathia, malar hypoplasia and a high-pitched voice, immunodeficiency, type II diabetes, and hypogonadism associated with male infertility and female subfertility. The aim of this report is to describe case of patient with BS who developed adenocarcinoma of the cecum, successfully treated by right colectomy. Case Report. A 40-year-old man underwent colonoscopy to investigate the cause of his diarrhea, weight loss, and anemia. The patient knew that he was a carrier of BS diagnosed at young age. The colonoscopy showed an expansive and vegetating mass with 5.5 cm in diameter, located within the ascending colon. Histopathological analysis of tissue fragments collected during colonoscopy confirmed the presence of tubular adenocarcinoma, and he was referred for an oncological right colectomy. The procedure was performed without complications, and the patient was discharged on the fifth postoperative day. Histopathological examination of the surgical specimen confirmed the presence of a grade II tubular adenocarcinoma (stage IIA). The patient is currently well five years after surgery, without clinical or endoscopic signs of relapse in a multidisciplinary approach for the monitoring of comorbidities related to BS. Conclusion. Despite the development of colorectal cancer to be, a possibility rarely described the present case shows the need for early screening for colorectal cancer in all patients affected by BS.

6.
Case Rep Surg ; 2015: 297450, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25977829

RESUMO

Introduction. Serrated adenomas of the appendix are rare and usually found during appendectomy or autopsies. The preoperative diagnosis of these tumors is uncommon. This report describes a case of a sessile serrated adenoma located in the appendix diagnosed by a screening colonoscopy and successfully treated by laparoscopic removal. Presentation of Case. An 86-year-old woman underwent colonoscopy to investigate the cause of her diarrhea, weight loss, and anemia. During the colonoscopy, an expansive and vegetating mass of 1.5 cm in diameter was identified, protruding through the appendicular ostium with slightly lateral growth to the cecum. The patient was referred for laparoscopic surgical resection due to the location of the lesion, which did not allow its removal by colonoscopy. She underwent wedge removal of the cecum without complications and was discharged on the 4th postoperative day. Histopathological examination showed the presence of a sessile serrated adenoma with an intramucosal adenocarcinoma. The patient is currently well one year after surgery, without endoscopic signs of relapse. Conclusion. Despite serrated adenomas being a possibility rarely described in appendix it should be recognized and properly treated because it is presenting a higher risk of cancer.

7.
Acta Cir Bras ; 28(11): 783-7, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24316746

RESUMO

PURPOSE: To evaluate the effects of peritoneal lavage with bupivacaine on survival and initial resistance of anastomosis on distal colon, performed under peritonitis or not. METHODS: Forty rats, weighing from 300 to 350 g (321.29 ± 11.3 1g), were randomly divided in four groups and underwent laparotomy and anastomosis on the distal colon six hours after induction of peritonitis by intraperitoneal injection of autologous fecal material or not. Group 1: No peritonitis and lavage with 3 ml NS; Group 2: No peritonitis and lavage with 8 mg.kg-1 (± 0.5 mL) of 0.5% bupivacaine added to 2.5 mL of NS; Group 3: Peritonitis and lavage with 3 ml NS; Group 4: Peritonitis and lavage with 8 mg.kg-1 (± 0.5 mL) of 0.5% bupivacaine added to 2.5 mL of NS. Necropsies were performed on the animals that died and the time of death was recorded. Surviving animals were submitted to euthanasia on the fifth post-operative day and Total Energy of Rupture biomechanical test (TER) was applied. RESULTS: Group 4 showed survival increase compared to Group 3, without statistical significance. Group 3 presented the smallest average TER, with statistical significance. CONCLUSION: Peritonitis increased mortality and influenced negatively the resistance of colic anastomosis in rats. Peritoneal lavage with bupivacaine increased anastomotic resistance.


Assuntos
Anestésicos Locais/uso terapêutico , Bupivacaína/uso terapêutico , Colo/cirurgia , Lavagem Peritoneal/métodos , Peritonite/terapia , Anastomose Cirúrgica , Animais , Modelos Animais de Doenças , Fezes , Masculino , Peritonite/mortalidade , Período Pós-Operatório , Distribuição Aleatória , Ratos , Ratos Wistar , Reprodutibilidade dos Testes , Taxa de Sobrevida , Fatores de Tempo , Resultado do Tratamento
8.
Rev. méd. Minas Gerais ; 23(4)out.-dez. 2013.
Artigo em Português | LILACS | ID: lil-704937

RESUMO

A dor neuropática pode ser decorrente de diversas causas, entre elas a schwannomatose (SCH), uma doença que acomete cerca de cinco mil brasileiros. A SCH é caracterizada por schwannomas múltiplos e intensamente dolorosos. O diagnóstico diferencial de SCH inclui especialmente as neurofibromatoses do tipo 1 e 2. Um caso típico de SCH, provavelmente o primeiro registrado no Brasil, é apresentado e discutido em detalhes e dois outros casos subsequentes são comparados quanto a determinados aspectos clínicos e radiológicos. Paciente feminina de 33 anos de idade foi admitida com queixas de dor e diminuição progressivada força no membro inferior esquerdo, havia cinco anos, associadas ao surgimento de nodulações muito dolorosas naquela região. Apresentava também duas manchas café com leite (<1 cm). A RNM detectou tumores de partes moles em região subcutânea e intracavitárias. Foram realizadas duas biópsias em regiões distintas e o exame microscópico de dois nódulos revelou células de Schwann envoltas por abundante estroma mixóide. O exame imuno-histoquímico mostrou marcação forte e difusa para proteína S-100. O exame ultraestrutural demonstrou nas áreas centrais células de Schwann, com restos membranosos intracitoplasmáticos e, focalmente, membrana basal redundante. A sintomatologia álgica, o padrão de crescimento neoplásico intraneural, com acentuado edema peritumoral, hialinização vascular e reatividade imuno-histoquímica para proteína S-100 nas células de Schwann no centro das lesões possibilitaram o diagnóstico de schwannomatose. O tratamento farmacológico para a dor foi a opção possível, obtendo-se remissão parcial da dor...


Neuropathic pain stems various sources including schwannomatosis (SCH), a disease that affects about five thousand Brazilians. SCH is characterized by multiple and intensely painful schwannomas. Differential diagnosis of SCH includes, especially, neurofibromatosis types 1 and 2. A typical case of SCH, possibly the first recorded in Brazil, is presented and discussed in detail and compared with two other subsequent cases with regards to selected clinical and radiological aspects. A 33 year-old female patient was admitted with pain and progressive loss of strength in the left lower limb for the past five years. These complaints were associated withthe appearance of very painful nodules in the same region. She also had two light brown (café-au-lait) spots (<1 cm). MRI detected soft tissue tumors in the subcutaneous and intracavitary regions. Two distinct biopsies of different regions and microscopic examination of two nodulesrevealed Schwann cells surrounded by abundant myxoid stroma. Immunohistochemical examination showed strong and diffuse markers of S-100 protein. Ultrastructural examination showed Schwann cells in the core areas with traces of intracytoplasmic membranes and foci of redundant basement membrane. The pain symptoms, the pattern of intraneural neoplastic growth with marked peritumoral edema, vascular hyalinization, and immunohistochemical reactivity for S-100 protein in Schwann cells in lesion cores suggested the diagnosis of schwannomatosis. Pharmacological pain treatment achieved partial remission of pain...


Assuntos
Humanos , Feminino , Adulto , Células de Schwann/ultraestrutura , Dor Facial/diagnóstico , Neurofibroma/complicações , Neurofibromatose 1 , Biópsia , Brasil , Diagnóstico Diferencial , Dor Facial/tratamento farmacológico
9.
Acta cir. bras ; 28(11): 783-787, Nov. 2013. tab
Artigo em Inglês | LILACS | ID: lil-695959

RESUMO

PURPOSE: To evaluate the effects of peritoneal lavage with bupivacaine on survival and initial resistance of anastomosis on distal colon, performed under peritonitis or not. METHODS: Forty rats, weighing from 300 to 350g (321.29±11.31g), were randomly divided in four groups and underwent laparotomy and anastomosis on the distal colon six hours after induction of peritonitis by intraperitoneal injection of autologous fecal material or not. Group 1: No peritonitis and lavage with 3ml NS; Group 2: No peritonitis and lavage with 8 mg.kg-1 (± 0.5 mL) of 0.5% bupivacaine added to 2.5 mL of NS; Group 3: Peritonitis and lavage with 3ml NS; Group 4: Peritonitis and lavage with 8 mg.kg-1 (± 0.5 mL) of 0.5% bupivacaine added to 2.5 mL of NS. Necropsies were performed on the animals that died and the time of death was recorded. Surviving animals were submitted to euthanasia on the fifth post-operative day and Total Energy of Rupture biomechanical test (TER) was applied. RESULTS: Group 4 showed survival increase compared to Group 3, without statistical significance. Group 3 presented the smallest average TER, with statistical significance. CONCLUSION: Peritonitis increased mortality and influenced negatively the resistance of colic anastomosis in rats. Peritoneal lavage with bupivacaine increased anastomotic resistance.


Assuntos
Animais , Masculino , Ratos , Anestésicos Locais/uso terapêutico , Bupivacaína/uso terapêutico , Colo/cirurgia , Lavagem Peritoneal/métodos , Peritonite/terapia , Anastomose Cirúrgica , Modelos Animais de Doenças , Fezes , Período Pós-Operatório , Peritonite/mortalidade , Distribuição Aleatória , Ratos Wistar , Reprodutibilidade dos Testes , Taxa de Sobrevida , Fatores de Tempo , Resultado do Tratamento
10.
J. coloproctol. (Rio J., Impr.) ; 33(3): 157-160, July-Sept/2013. ilus
Artigo em Inglês | LILACS | ID: lil-695210

RESUMO

Pelvic recurrence after resection of rectal adenocarcinoma is a feared complication and is associated with a worse prognosis and low resectability rates. The differential diagnosis is difficult, as biopsy is seldom performed preoperatively. We report two cases of desmoid pelvic tumor after resection of rectal adenocarcinoma. Therapeutic options and literature review are described.


O aparecimento de tumor pélvico após ressecção de adenocarcinoma de reto é complicação temida e está associado à pior prognóstico e baixos índices de ressecabilidade. O diagnóstico diferencial é difícil, pois o diagnóstico histológico usualmente não é realizado no pré-operatório. São relatados dois casos em que houve o aparecimento de tumor pélvico após a ressecção de adenocarcinoma de reto, com diagnóstico histológico de tumor desmóide. As condutas adotadas e revisão da literatura são descritas.


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Idoso , Neoplasias Retais , Adenocarcinoma , Neoplasias Pélvicas/diagnóstico por imagem , Recidiva , Fibromatose Agressiva/patologia , Fibromatose Agressiva/terapia , Diagnóstico Diferencial
11.
J Orofac Pain ; 27(2): 135-41, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23630685

RESUMO

AIMS: To identify potential predictors of self-reported sleep bruxism (SB) within children's family and school environments. METHODS: A total of 65 primary school children (55.4% males, mean age 9.3 ± 1.9 years) were administered a 10-item questionnaire investigating the prevalence of self-reported SB as well as nine family and school-related potential bruxism predictors. Regression analyses were performed to assess the correlation between the potential predictors and SB. RESULTS: A positive answer to the self-reported SB item was endorsed by 18.8% of subjects, with no sex differences. Multiple variable regression analysis identified a final model showing that having divorced parents and not falling asleep easily were the only two weak predictors of self-reported SB. The percentage of explained variance for SB by the final multiple regression model was 13.3% (Nagelkerke's R² = 0.133). While having a high specificity and a good negative predictive value, the model showed unacceptable sensitivity and positive predictive values. The resulting accuracy to predict the presence of self-reported SB was 73.8%. CONCLUSION: The present investigation suggested that, among family and school-related matters, having divorced parents and not falling asleep easily were two predictors, even if weak, of a child's self-report of SB.


Assuntos
Bruxismo do Sono/diagnóstico , Bruxismo do Sono/etiologia , Meio Social , Nível de Alerta , Criança , Divórcio , Família , Feminino , Humanos , Masculino , Análise de Regressão , Fatores de Risco , Instituições Acadêmicas , Autorrelato , Sensibilidade e Especificidade , Sono
12.
Int J Surg Case Rep ; 4(3): 322-4, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23416499

RESUMO

INTRODUCTION: Bowel perforation with free peritoneal air is a rare complication of Crohn's disease (CD). PRESENTATION OF CASE: We report a case of a 36 year-old male patient, with history significant for CD and he presented to the emergency room with a free peritoneal perforation, which was diagnosed by abdominal X-ray and confirmed by CT scan. The patient underwent a laparotomy surgery; however, no site of perforation was identified. The surgical approach was to clean the cavity, close the abdominal wall and administer antibiotic therapy. He demonstrated good early and late postoperative outcomes. DISCUSSION: We report a rare case of free perforation to the peritoneum in a patient with CD. The most likely hypothesis is that it was a micro-colonic perforation. Antibiotic therapy and a conservative surgical approach without colon resection can be performed and it is reported in the literature. CONCLUSION: Emergency conditions in CD may result in significant morbidity, but are normally associated with low mortality, if identified and treated properly.

13.
J. coloproctol. (Rio J., Impr.) ; 31(4): 372-377, Oct.-Dec. 2011. ilus, tab
Artigo em Inglês | LILACS | ID: lil-623489

RESUMO

There is a clear association between chagasic megaesophagus and the esophageal cancer. On the other hand, the association between chagasic megacolon and intestinal neoplasm is uncommon. There are only a few cases described in literature. We selected two cases of colorectal adenocarcinoma associated with adenoma from 2000 to 2011, which are added to the four patients already described by this group. The mean age of the patients, was 68.5 years. Both had been submitted to surgical resection of the neoplasm. Survival rates ranged and were directly related to tumor staging at the time of diagnosis. In this context, we report our case series and reviwed the corresponding literature, especially the clinical and epidemiological aspects of this rare association. (AU)


Há uma clara associação entre megaesôfago por doença de Chagas e o câncer esofágico. Ao contrário, tal relação, entre megacólon chagásico e neoplasias do intestino grosso é, reconhecidamente, incomum. Existem poucos casos relatados na literatura. Destacamos, entre 2000 e 2011, dois casos, sendo ambos adenocarcinomas colorretais e associados a adenomas, que se somam aos outros quatro já descritos por este grupo. A média de idade dos pacientes, foi de 68,5 anos. Todos foram submetidos à ressecção cirúrgica da neoplasia. A sobrevida foi variável e diretamente relacionada ao estádio do tumor no momento do diagnóstico. Dentro desse contexto, relatamos essa série de casos e revisamos a literatura correlata, com relação aos aspectos clínicos e epidemiológicos dessa rara associação. (AU)


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Doença de Chagas , Neoplasias do Colo , Megacolo/patologia , Reto/patologia , Colonoscopia , Colectomia , Megacolo/diagnóstico
14.
Rev. CEFAC ; 8(4): 509-517, out.-dez 2006. tab, graf
Artigo em Português | LILACS | ID: lil-439828

RESUMO

Objetivo: investigar a possível relação do Pico de Fluxo Expiratório (PFE) com o Tempo Máximo deFonação (TMF) em pacientes asmáticos. Métodos: a pesquisa enfocou 16 indivíduos com o diagnósticode asma pura, sendo 9 do gênero feminino e 7 do gênero masculino, atendidos no serviçoambulatorial de pneumologia do Hospital Júlia Kubitschek em BH. A equipe de pneumologia diagnosticou,classificou a asma e realizou o teste PFE. Posteriormente os pacientes foram submetidos àextração de tempo Máximo de Fonação (TMF) para os sons /a/, /i/, /u/, /e áfono/, /e sonoro/, /s/ e /z/.Resultados: dos pacientes atendidos havia 12,50% (2) com asma tratada, 18,75% (3) com asma persistenteleve, 43,75% (7) com asma persistente moderada, 6,25% (1) com asma moderada grave e18,75% (3) com asma persistente grave. Foi observado que quando o TMF encontrava-se reduzidoocorria também uma redução do PFE e quando havia um aumento do TMF era encontrado no PFEvalor também maior. Conclusão: foi possível observar uma associação e uma correlação entre asmedidas TMF e PFE que sugerem uma relação direta dessas medidas.


Purpose: to investigate the possible relationship between Expiratory Flow Peak (EFP) and MaximumPhonation Duration (PMD) for asthmatic patients Methods: the research focused on 16 individualsdiagnosed with pure asthma, where 9 were female and 7 were males, treated at the pneumologyclinical services of Júlia Kubitschek Hospital. The pneumology team diagnosed, classified the asthmaand performed the EFP test. The patients were submitted afterwards to PMD speech therapy evaluation.Results: within the treated patients there were 12.50% (2) with treated asthma, 18.75% (3) with lightpersistent asthma, 43.75 % (7) with moderate persistent asthma, 6.25% (1) with severe moderateasthma and 18.75% (3) with severe persistent asthma. It was found that when PMD had decreasedthere was a decrease in EFP as well, and that when there was an increase of PMD the EFP valuewould also increase. Conclusion: it was possible to note a relation and a correlation between PMDand EFP measures, suggesting a direct relation between these measurements.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Asma/fisiopatologia , Fonação/fisiologia , Pico do Fluxo Expiratório/fisiologia , Asma/classificação , Asma/diagnóstico , Medidas de Volume Pulmonar , Fonética , Fatores de Tempo
15.
Rev. bras. med. otorrinolaringol ; 6(1): 20-5, set. 1999. tab, graf
Artigo em Português | LILACS | ID: lil-253514

RESUMO

O presente estudo teve como objetivo avaliar o desempenho auditivo de crianças de três a quatro anos, através das medidas de imitância acústica (MIA), que são úteis em triagem auditiva, pois detectam alterações no funcionamento da orelha média que podem prejudicar o desenvolvimento da linguagem em crianças. Realizou-se avaliação otológica e MIA em 30 crianças, sendo 13 (43,3 por cento) do sexo feminino e 17 (56,7 por cento) do sexo masculino. Na avaliação otológica, verificou-se que 27 crianças (90 por cento) apresentaram otoscopia normal e 3 (10 por cento) apresentaram otoscopia alterada. Nas curvas timpanométricas, verificou-se que 21 (70 por cento) orelhas direitas e 19 (63,3 por cento) orelhas esquerdas apresentaram curva tipo A; 4 (13,3 por cento) orelhas direitas e 6 (20 por cento) orelhas esquerdas curva tipo B; e 5 (16,7 por cento) orelhas direitas e esquerdas curva tipo C. Os valores da compilância estática variaram de 0,0 ml a 1,8 ml, sendo que os valores médios da compilância estática variaram de 0,40 a 0,63 ml. Os reflexos acústicos estiveram presentes e em níveis normais de audição na maioria das crianças, não sendo encontradas diferenças estatisticamente significantes quanto a variável faixa etária. Verificamos que as MIA são eficazes na realização de triagem auditiva infantil, permitindo-nos identificar pequenas alterações auditivas e realizar os encaminhamentos e orientações necessários.


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Testes de Impedância Acústica , Orelha Média/fisiologia , Testes Auditivos , Reflexo Acústico , Transtornos da Audição/diagnóstico
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